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The human body has its own physiologic mechanisms of sensing changes in blood pressure and controlling blood pressure. The major part of this system is located in the brain and also in the walls of the carotid arteries, located in the neck. Pressure sensors called baroreceptors are located on the carotid artery and in the carotid sinus. These sensors measure and report blood pressure to the brain; where it is compared to the needs of the body. For example, higher blood pressure is good for exercising, while lower blood pressure is appropriate during sleep or other periods of reduced activity. If the brain senses higher-than-needed blood pressure from the baroreceptors, it acts to lower blood pressure by sending signals to various parts of the body to lower blood pressure, including the heart, blood vessels and kidneys.
The “baroreflex” or “baroreceptor reflex” are terms used to describe the body's rapid response system for dealing with changes in blood pressure.
The Rheos hypertension treatment pivotal clinical trial will evaluate whether an investigational implanted device, designed to electrically activate the baroreflex, can help control high blood pressure.
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